Molecular Simulation and Biochemical Studies Support an Elevator-type Transport Mechanism in EIIC
نویسندگان
چکیده
منابع مشابه
simulation and experimental studies for prediction mineral scale formation in oil field during mixing of injection and formation water
abstract: mineral scaling in oil and gas production equipment is one of the most important problem that occurs while water injection and it has been recognized to be a major operational problem. the incompatibility between injected and formation waters may result in inorganic scale precipitation in the equipment and reservoir and then reduction of oil production rate and water injection rate. ...
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The active transport process, so important in cell function, has been studied in the past with intact cells. Models which have arisen from this work all depend on: first, a specific protein to recognize the substrate; second, translocation of the substrate across the cell membrane; third, release of substrate within the cell and restoration of the system to its initial state. These steps are ad...
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the accurate mechanism of how EIIC transports a sugar has not been clearly demonstrated yet. To investigate more detailed and accurate transportation mechanisms, we performed collective variable-based steered molecular dynamics (CVSMD) simulations. Our simulation shows the spontaneous transportation of the sugar toward the opposite side of the membrane with the preserved H-bonding interactions,...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2017
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.04.040